Microfabricated Cortical Neuroprostheses

Name: Microfabricated Cortical Neuroprostheses
Brand: EPFL Press English Imprint
SKU: 9781439837542
Price: 84.5 CHF
Availability: InStock
ISBN: 978-1-43983-754-2

de André Mercanzini (auteur), Philippe Renaud (auteur)

Collection : Micro- and nanotechnology

juin 2010

Livre papier format 160 x 240 146 pages Indisponible	68,70 €
eBook 146 pages	Indisponible

Medias

Présentation

The use of neural implants for stimulation and recording show excellent promise in restoring certain functions to the central nervous system; and neuroprostheses remain one of the most important tools of neuroscientists for the elucidation of the brain's function. Ailments such as Parkinson's disease, obesity, blindness, or epilepsy are being studied from this angle. Development of better electrodes for recording and stimulation is therefore critical to ensure continuing progress in this field. This book addresses one of the main clinical complications of the use of electrodes, namely the reaction of the neurological tissue in the immediate vicinity of implanted devices. The authors describe new techniques for the assessment of this phenomenon, as well as new microfabrication techniques that impede the inflammatory response of the brain that tends to limit the lifetime and reduce the effectiveness of these devices. The measurement protocols and improved fabrication protocols described will become standard tools in the future of neuroprostheses.

Sommaire

Introduction – Scientific and clinical context – Problem statement: the tissue reaction to implanted neuroprostheses – Review of past research – Technology position with respect to state of the art – Research objectives – Limitations – Structure of the book
Microfabrication Techniques for Neuroprostheses – Microelectrode arrays – Microfluidic channels – Neural Recording and Stimulation – The Neurophysiological basis of recording – The neurophysiological basis of stimulation – Applications of neural recording – Applications of neural stimulation – In vivo Electrical Impedance Spectroscopy – Materials and methods – Results – Discussion -Controlled Release Drug Coatings – Materials and methods – Results – Discussion – Conclusion
Summary of main results – Significance – Future Perspectives – References – Index